Publications

View selected publications about the research we have conducted at the Pediatric Exercise & Genomics Research Center:

• Lu KD, Billimek J, Bar-Yoseph R, Radom-Aizik S, Cooper DM, Anton-Culver H. Sex Differences in the Relationship Between Fitness and Obesity on Risk for Asthma in Adolescents. J Pediatr 176: 36-42, 2016.

• Radom-Aizik S, Cooper DM. Bridging the Gaps: the Promise of Omics Studies in Pediatric Exercise Research. Pediatr Exerc Sci. 28(2):194-201, 2016.

• Falk B, Haddad F, Klentrou P, Ward W, Kish K, Mezil Y, Radom-Aizik S. Differential Sclerostin and Parathyroid Hormone Response to Exercise in Boys and Men. Osteoporos Int. 27(3):1245-9, 2016.

• Cooper DM, Leu SY, Taylor-Lucas C, Lu K, Galassetti P, Radom-Aizik S. Cardiopulmonary Exercise Testing in Children and Adolescents with High Body Mass Index. Pediatr Exerc Sci. 28(1):98-108, 2016.

• Lu KD, Manoukian K, Radom-Aizik S, Cooper DM, Galant SP. Obesity, Asthma and Exercise in Child and Adolescent Health. Pediatr Exerc Sci. 2015.

• Liem RI, Onyejekwe K, Olszewski M, Nchekwube C, Zaldivar FP, Radom-Aizik S, Rodeghier MJ, Thompson AA. The Acute Phase Inflammatory Response to Maximal Exercise Testing in Children and Young Adults with Sickle Cell Anaemia. Br J Haematol. 171(5):854-61, 2015.

• Cooper DM, Radom-Aizik S. The Common Fund Initiative and Its Implication for Advancing Exercise and Physical Activity Research in Child Health. Pediatr Exerc Sci. 27(3):297-300, 2015.

• Shin HW, Barletta B, Yoonessi L, Meinardi S, Leu SY, Radom-Aizik S, Randhawa I, Nussbaum E, Blake DR, Cooper DM. Quantification of Aerosol Hydrofluoroalkane HFA-134a Elimination in the Exhaled Human Breath Following Inhaled Corticosteroids Administration. Clin Transl Sci. 28(5):445-50, 2015.

• Horvath P, Oliver SR, Zaldivar FP, Radom-Aizik S, Galassetti PR. Effects of Intravenous Glucose and Lipids on Innate Immune Cell Activation in Healthy, Obese and Type 2 Diabetic Subjects. Physiol Rep. 12;3(2), 2015.

• Ashish N, Bamman MM, Cerny FJ, Cooper DM, D'Hemecourt P, Eisenmann JC, Ericson D, Fahey J, Falk B, Gabriel D, Kahn MG, Kemper HC, Leu SY, Liem RI, McMurray R, Nixon PA, Olin JT, Pianosi PT, Purucker M, Radom-Aizik S, Taylor A. The Clinical Translation Gap in Child Health Exercise Research: A Call for Disruptive Innovation. Clin Transl Sci. 8(1):67-76, 2015.

• Radom-Aizik S, Zaldivar Jr FP, Haddad F, and Cooper DM. Impact of Brief Exercise on Circulating Monocyte Gene and MicroRNA Expression: Implications for Atherosclerotic Vascular Disease. Brain, Behavior and Immunity 39: 121-129, 2014.

• Cooper DM, Leu S-Y, Galassetti P, and Radom-Aizik S. Dynamic Interactions of Gas Exchange, Body Mass and Progressive Exercise in Children. Med Sci Sports Exerc 46: 877-886, 2014.

• Radom-Aizik S, Zaldivar FP, Nance DM, Haddad F, Cooper DM, and Adams GR. Growth Inhibition and Compensation in Response to Neonatal Hypoxia in Rats. Pediatr Res 74: 111-120, 2013.

• Radom-Aizik S, Zaldivar F, Haddad F, and Cooper DM. Impact of Brief Exercise on Peripheral Blood NK Cell Gene and MicroRNA Expression in Young Adults. J Appl Physiol 114: 628-636, 2013.

• Galassetti P and Riddell MC. Exercise and Type 1 Diabetes (T1DM). Compr Physiol 3: 1309-1336, 2013.

• Horvath P, Oliver SR, Ganesan G, Zaldivar FPJ, Radom-Aizik S, and Galassetti PR. Fasting Glucose Level Modulates Cell Surface Expression of CD11b and CD66b in Granulocytes and Monocytes of Patients with Type 2 Diabetes. J Investig Med 61: 972-977, 2013.

• Olshansky E, Lakes KD, Vaughan J, Gravem D, Rich JK, David M, Nguyen H, and Cooper D. Enhancing the Construct and Content Validity of Rating Scales for Clinical Research: Using Qualitative Methods to Develop a Rating Scale to Assess Parental Perceptions of Their Role in Promoting Infant Exercise. Int J Educ Psychol Assess 10: 36-50, 2012.

• Radom-Aizik S, Zaldivar F, Leu S-Y, Adams GR, Oliver S, and Cooper DM. Effects of Exercise on MicroRNA Expression in Young Males Peripheral Blood Mononuclear Cells. Clin Transl Sci 5: 32-38, 2012.

• Oliver SR, Hingorani SR, Rosa JS, Zaldivar FP, and Galassetti PR. Synergistic Effect of Obesity and Lipid Ingestion in Suppressing the Growth Hormone Response to Exercise in Children. J Appl Physiol 113: 192-198, 2012.

• Galassetti P. Inflammation and Oxidative Stress in Obesity, Metabolic Syndrome and Diabetes. Exp Diabetes Res 2012: 943706, 2012.

• Adams GR, Zaldivar FP, Nance DM, Kodesh E, Radom-Aizik S, and Cooper DM. Exercise and Leukocyte Interchange Among Central Circulation, Lung, Spleen and Muscle. Brain, Behavior, and Immunity 25: 658-666, 2011.

• Kodesh E, Zaldivar F, Schwindt C, Tran P, Yu A, Camilon M, Nance DM, Leu S-Y, Cooper D, and Adams GR. A Rat Model of Exercise-Induced Asthma: A Nonspecific Response to a Specific Immunogen. Am J Physiol Regul Integr Comp Physiol 300: R917-R924, 2011.

• Radom-Aizik S, Zaldivar F, Oliver S, Galassetti P, and Cooper DM. Evidence for MicroRNA Involvement in Exercise-Associated Neutrophil Gene Expression Changes. J Appl Physiol 109: 252-261, 2010.

• Ahmad I, Nemet D, Eliakim A, Koeppel R, Grochow D, Coussens M, Gallitto S, Rich J, Pontello A, Leu S-Y, Cooper DM, and Waffarn F. Body Composition and Its Components in Preterm and Term Newborns: A Cross-Sectional, Multimodal Investigation. Am J Hum Biol 22: 69-75, 2010.

• Adams GR. Insulin-Like Growth Factor | Signaling in Skeletal Muscle and the Potential for Cytokine Interactions. Med Sci Sports Exerc 42: 50-57, 2010.

• Buchowicz B, Yu T, Nance DM, Zaldivar FP, Cooper DM, and Adams GR. Increased Rat Neonatal Activity Influences Adult Cytokine Levels and Relative Muscle Mass. Pediatr Res 68: 399-404, 2010.

• Eliakim A, Nemet D, Ahmad I, Zaldivar F, Koppel R, Grochow D, Waffarn F, and Cooper DM. Growth Factors, Inflammatory Cytokines and Postnatal Bone Strength in Preterm Infants. J Pediatr Endocrinol Metab 22: 733-740, 2009.

• Bodell PW, Kodesh E, Haddad F, Zaldivar FP, Cooper DM, and Adams GR. Skeletal Muscle Growth in Young Rats Is Inhibited by Chronic Exposure to IL-6 but Preserved by Concurrent Voluntary Endurance Exercise. J Appl Physiol 106: 443-453, 2009.

• Gravem D, Lakes KD, Teran L, Rich J, Cooper D, and Olshansky E. Maternal Perceptions of Infant Exercise in the Neonatal Intensive Care Unit. J Obstet Gynecol Neonatal Nurs 38: 527-533, 2009.

• Radom-Aizik S, Zaldivar F, Leu S-Y, and Cooper DM. Brief Bout of Exercise Alters Gene Expression in Peripheral Blood Mononuclear Cells of Early- and Late-Pubertal Males. Pediatr Res 65: 447-452, 2009.

• Shin H-W, Umber B, Meinardi S, Leu S-Y, Zaldivar F, Blake D, and Cooper D. Acetaldehyde and Hexanaldehyde from Cultured White Cells. Journal of Translational Medicine 7: 31, 2009.

• Radom-Aizik S, Zaldivar F, Leu S-Y, Galassetti P, and Cooper DM. Effects of 30 Min of Aerobic Exercise on Gene Expression in Human Neutrophils. J Appl Physiol 104: 236-243, 2008.

• Radom-Aizik S, Leu S-Y, Cooper DM, and Zaldivar Jr F. Serum from Exercising Humans Suppresses T-Cell Cytokine Production. Cytokine 40: 75-81, 2007.

• Cooper DM, Radom-Aizik S, Schwindt C, and Zaldivar F. Dangerous Exercise: Lessons Learned from Dysregulated Inflammatory Responses to Physical Activity. J Appl Physiol 103: 700-709, 2007.

• Zaldivar F, Eliakim A, Radom-Aizik S, Leu S-Y, and Cooper DM. The Effect of Brief Exercise on Circulating CD34+ Stem Cells in Early- and Late-Pubertal Boys. Pediatr Res 61: 491-495, 2007.

• Ischander M, Zaldivar F, Eliakim A, Nussbaum E, Dunton G, Leu S-Y, Cooper DM, and Schneider M. Physical Activity, Growth and Inflammatory Mediators in BMI-Matched Female Adolescents. Med Sci Sports Exerc 39: 1131-1138, 2007.